Just used Launcher and disabled the settings for MultiSampling and Ansisotrophy Filter on a start from scratch and new discovery of hardware and go figure, disabling this settings sets them to 1 on the INI, not 0. From this guide https://wiki.step-project.com/Guide:SkyrimPrefs_INI/Display it says that 0 is off and 1 is low setting? May be you need to be more specific about the off setting for this entries.