I'd hold off on setting up groups for a while, I'm testing currently and there may be some changes made to current rules. For one ICAIO & RDO are going to be moved to the default group, ICAIO might even be going to the same group as Cutting room floor. Mainly because of all the landscape and navmesh changes it makes. Its pretty clear when you have to move all location changes after the mod, that its an issue. There is no reason for it to be as high up as it is, it would be like putting verdant or landscape fixes for grass mods in the same position. As for loading both after Alt start, not really needed, there are only a handful of records that conflict. RDO is pretty safe there but ICAIO has too many conflicts.