NihilCredo

Just a warning, the author has decided to slap Oblivion gates straight in the middle of the cities for some reason, and he loudly refused to make them optional... :/

I wouldn't say it's "not as versatile" as Wrye Bash. WB has some important advanced functionality (Bashed Patching first and foremost), but in terms of purely managing mods, Mod Organizer is far more powerful. Mod isolation alone, with all the profile managing it allows, is a HUGE killer feature on its own (just consider that you can go back to a clean Skyrim profile in three clicks, without having to move any files or actually 'uninstall' anything). Oh, and it doesn't actually need a background process, it's got a button that will create for you a Skyrim shortcut which loads the modding profile through a SKSE plugin or a couple other methods.

Yeah I'm in the same boat as Faitmaker. Without SkyBoost, my OC'd 5770 can handle STEP Skyrim pretty well, but throw in an ENB DoF on top of that and it spends a bit too much time in the low 20s for my tastes... but I have trouble getting used again to playing without bokeh DoF, it feels like a huge step back in immersion. Alexander says that he'll only make a 1.5 version if Beth doesn't make a new patch within the next "20-30 days". The Witcher 1 (finally getting around to this classic) should easily carry me through then, and in the meanwhile I can use that time to tweak my mod setup.

Can you just point this to any skyrim.ini and skyrimprefs.ini files in any folder? This would make it play well with Mod Organizer's profiles.