I have heard people say that this won't make any difference if you have less than 1G of vram, but I'm here to say that it does. I run in a laptop....1.5Ghz quad core with a radeon 6520g (512 dedicated and sharable up to 2G). I was running on high settings at 1024x576 and getting about 25fps on average. However, I would get a lot of stuttering and quite a few random CTDs. After using the memory patch I still only get 25fps, but I don't have any stuttering and not one CTD yet after 4 hours of play. Even though my fps didn't change it feels like it went up by at least 10 because if how smooth it runs now.
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