LOOT and BOSS need a lot of change in the load order. I have done this week a new installation with STEP extended, REGS and REQUIEM then run BOSS. First I use the userlist rules modifications from REGS, second those from Smile44 in BUM. After that, using WB I have to modify the load order of a lot of plugins ( master not in the right order) directly in MO. And I lock the load order. The game seems to run OK. STEP Extended, for example need some tweaking in the install order : immersive animation need to be before XP32, maybe you don't need some sound mods ( read the Nexus page of AOS). You need to read the Neovalen SR:LE page, he gives a lot a of information on the installation. The installation of enboost and the ini is lacking in the STEP page, you have to read the text from Boris.