I personally feel like LAL is necessary if you're following a guide of this scale and you want to start a new game without having to do the whole intro. That being said, I remove a lot of the ones you've mentioned specifically, and several (about 25% of the guide) more. The main thing is editing the main CR patch - it still applies to a lot of what I do install, so I find it easier to rip out what I don't need. It's just a matter of removing the records to plugins you don't use, which is covered in the guide's Troubleshooting section. Aside from that, I only use half of the NPC retexture mods so I created my own CR for that, using the existing one as a guide. SSEEdit is your friend (and sometimes enemy).