BishyT

Yes, I make sure the Automatic Archive Invalidation is checked every time I go to Manage Profiles. I also make sure that I actually have the profile highlighted when I do that (I only have one profile, default).

I believe I do. There's even a "Oblivion - Invalidation.bsa" file in the Archives tab. Ok, I fixed the problem halfway through typing this message. I went to the workarounds screen and pressed the "Back-date BSAs" button, and now Darnified UI seems to be working (haven't tested the body mods yet, but i'm assuming they'll work too). It seems that the Archive Invalidation wasn't working as intended and needed a little extra push.

I've been encountering some issues recently with Mod Organizer when it comes to mods that don't use/require .esp files. For example, Darnified UI 132 (.7z version) doesn't use an esp file, as it's intended to be used as a replacer. Then there are body replacers like Robert's Male Body and HGEC. Although they include .esp files, they're not nessecarily needed, and it's also recommended that the .esp files not be used alongside Oblivion Character Overhaul v2 to avoid conflicts. Anyways, i'm using the Steam version of Oblivion GOTY with OBSE. I know that OBSE is working because Blockhead works (allowing me to move the camera about in chargen). I know that the Mod Organizer OBSE hook is working, as Oblivion Character Overhaul v2 will work. However, neither Darnified UI nor the body replacers i'm using have any effect, and the only thing they have in common is that they're not using .esp files. Has anyone else experienced this problem? I'm using the latest version of MO, 1.2.11.

I think I might know what's causing the problem, thanks to the "You Can Now Open NXM Files Using Multiple Programs" thread. I was having the same problem as sargetao. I previously had OBO installed (with nexus links working) before uninstalling it to try out both NMM and OBMM instead. I then switched back to OBO only to find the nexus links not working. That thread you linked to mentioned the nxmhandler.exe. I looked at it, and it turns out that the primary handler was still set to my original OBO installation (I had installed it into a previous place). So I clicked "register active", and now nexus links work perfectly.