No SKSE Ran fine before i installed mod organizer i played skyrim for like 3 months Using SKSE. after the installation of MO which happened only yesterday, the only way to play skyrim with SKSE is through the mod organizer :/. and i already have full permissions and control over my skyrim and MO directories perhaps load order conflict between Vanilla loadorder and MO's? Reinstalled SKSE several times both Manual and with a binary file, still no luck.