For some reason running Loot through MO has been causing crashes for me on startup, before it completes loading of all the mods. LOOT loads just fine outside of MO, but even the "Core Fixes and Base UI" profile crashes - as does my Vanilla profile most of the time (sometimes it loads, sometimes it doesn't, with no changes made). I am using the legacy MO with NMM fixes as suggested in the guide, and have the most recent files for this version.