I just started having an issue (played the game fine, save, quit game, MO2 still running, literally came back a few hours later, restart game and issue happens, no new mods or changes made) All plugins are checked in the profile I'm using, but when I go to load a save, I get the "save relies on content no longer available..." message and it indicates that basically all mods (update, DB, hearthfires, etc) are not present (I checked - they are still there). When I go back to the MO2 pane, all plugins are still checked (including those that it said were not present). This is true for all the saves down the list. When I check the profile txt files (modlist, plugins, etc) it seems to indicate that everything is still there. I've checked my paths under settings, everything seems correct; MO2, usvsf, skyrim itself, etc are all excluded from my AV. I cleared out my log folder, ran log level as debug under diagnostics, when I exited out, I had a usvfs log with a bunch of info in it, so I don't think it's being blocked. I feel like it's some simple fix (hopefully) that I'm just missing (like an ini file got changed somehow); it's almost like it's not loading up the right profile or something. Any help or advise would be truly appreciated. Thanks