Fabricated101

Hey, so recently MO2 hasn't been able to run any of my programs, (FNIS, SKSE, Body Editor, etc.) Every time I would click run, a blank box would appear and MO would not respond and be forced to quit. I don't know what's causing the problem. Weird thing is I was playing before this happened. I save the game and quit. Was gone for about an hour or so, and then I come back and this problem started happening. Any ideas as to what I need to do to fix this? I uninstalled and reinstalled MO but that didn't fix the problem. Any help would be great.