I am experiencing the same issues with using MO2 and SSE. I clean-installed last night, have a pretty minimal load order, and everything was fine up until I installed Mator Smash and made a smash patch (don't know if that has anything to do with my issues). Then I go to SKSE in MO2 and click start. Small black window flashes as normal, but it's brief (half a second) and the game stops before it even starts. Running the latest (2.1.2) standalone version of MO2. Any suggestions or assistance would be helpful. edit: To clarify: I rebooted PC, Steam, MO2 multiple times. Also tried removing SKSE from executables in MO2, restarted MO2, SKSE is automatically back in executables after restarting, same results.