Guide:AMD Radeon Graphics

NOTE

Follow the game guide in all respects otherwise, but disable Vsync and FPS limiters in the game INI and in any other sources. They are redundant and could cause issues if set.

AMD Radeon Adrenalin

The following configuration works well to alleviate stutter during gameplay on higher-end systems. The issue is not caused by poor performance but rather timings in the frame buffer and how it plays with the game engine. These settings may generally apply to all AMD graphics where there is overlap, so give them a try to resolve issues. Since AMD's vsync is enabled here, it should be DISABLED in BethINI or SkyrimPrefs.ini.

SSE Display Tweaks

Try the following settings for SkyrimSE:SSE Display Tweaks:

Fullscreen=false
Borderless=true
EnableVSync=true
EnableTearing=true
SwapEffect=flip_sequential

Set the following to your monitor's refresh rate. Since frame rates are being limited here, the FPS limiter should be DISABLED in BethINI or Skyrim.ini.

MaximumRefreshRate=144
FramerateLimit=144