Uh.. does spINI not do that? It uses the Docs ones instead? Keyboard's a simple plug-and-play $10 base offering. Not really the kind of thing I expect to find issues with. Drivers... I'm running a 7770, and runs as expected in many games. ETS2 (though I'm currently having a mod crash issue with that too, as of today), KSP, Minecraft & it's many modpacks, XCOM, Deus Ex: HR, lots of older stuff. I've had no issues I can directly relate to gpu drivers. OK, so I hunted up the spINI files and the MO profiles folder, dumped them where they belong. No change. Further edit: does Skyrim Vanilla through MO running 100% fine rule out the local files served by Steam?