I am having the same problem as thebluebridgetroll I can not get NMM to handle Fallout4's mods. I ran the "nxmhandler.exe" tool and it is set up properly. I even watched Gophers video to make sure I had not done something stupid and its exactly as it should be yet every time I try to download a Fallout 4 mod Mod Organizer opens and tells me it is not set up to handle mods for that game. I ha ve also tried it with Witcher 3 and its the same thing, Mod Organizer opens and tells me its not set up to handle Witcher 3 mods. I have tried changeing the drive to the same one I have Mod Organizer on but it makes no difference it just wont work for me. has anyone got any advice or sugestions I can try please.