Yes, it's enabled, that doesn't seem to be the problem, I've used FNIS before, the thing is that I can't get it to run. Thanks, but sadly that hasn't been much help, as the post from tannin says, I'd need to run FNIS to avoid SKSE being "canceled by plugin", but the problem is that FNIS is also impossible to run because of this, and I don't remember ignoring any warning like the one mentioned in that post either, I always run FNIS pretty much any time I do any changes to anything. Though now I'm certain the problem is with my FNIS, I tried disabling it and sure enough SKSE managed to run (well kinda, it CTDd on the main menu, but at least it opened), I'll try reinstalling the older version and see if that works. EDIT: yup, I just reinstalled v5.5 and everything is running again, this was more than likely a screw up on my part when trying to update to the latest version.