It's interesting you mentioned the 4GB enabler. Although it would seem logical to count that out - as you stated - I do believe I read somewhere yesterday that reverting back to the original 4GB had stabilized someone's game on Windows 10. Like many folks, I am using the updated version of the enabler, found here: https://www.nexusmods.com/newvegas/mods/55061/ They recommended switching to this one: https://www.nexusmods.com/newvegas/mods/35262 How or why this helped some Windows 10 user, I have no idea. And I can't say with any certainty that this actually worked. The discussion on this was brief. Keep in mind my 4GB launcher came from the NVSE silverlock site. Thoughts? Would this be worth trying? It wouldn't be that difficult to start another dummy profile in MO and create a launcher for it with my current load order and game save. Regarding my video driver, I double checked yesterday and I am indeed up to date, using Nvidia's 355.82 game ready driver for Windows 10. Could this driver be the issue? Anyway, here's how everything went last night. I went into my 4GB exe and my Mod Organizer exe and set both to run as administrator. I crashed twice within a half hour; once when the game was loading assets and the other at an infinite loading screen. This is with my ENB enabled, by the way. This is where I decided to spend the rest of my night researching trying to get any ENB to play nice with Windows 10. Firstly, running on Windows 10, the only way to get the game to launch without an error code was to delete the dxgi.dll and dxgi.fx from my root folder. Doing so causes the game to launch and run, but ultimately crash like crazy. The odd thing is, and this is why I wonder if this is even an ENB issue at all, my game doesn't struggle at all before it crashes. Don't ENB issues generally present themselves with a lot of FPS drops before CTD'ing? That isn't happening here. My game is silky smooth before I crash. Now, my next step was to run my game in Windows 8 compatibilty mode, but there is a fundamental problem with ENB's and Compatibility Mode right now. When changing my 4GB launcher to run on Windows 8 Compatibility, with my ENB enabled, the game launches and runs, but I get no picture whatsoever. All I get is a black screen with sound. This goes for when I reinstated the two DLL's I deleted for running in Windows 10, and also when I launch in Windows 7 compatibilty. I can not figure out a way, any way at all, to get an ENB to work in Compatibility Mode. Period. So that leads us to the final step of the equation: running the game either with the injector version of the ENB or running without ENB's at all. I absolutely adore how this ENB runs and looks so I'd really rather keep it. I tried replacing the wrapper with the injector to see if that would help, but holy smokes, I literally have NO CLUE how to properly install and launch an injector ENB. I don't know which files fo remove and which to replace. I tried running the injector exe, adding FNV4GBexe to the injector.ini before hand, and the ENB is both not recognized and doesn't work. A very in depth thread I found last night said the injector was the solution for the "black screen" error so I'd love to know how to use this properly before eliminating ENB's all together from the equation. TLDR: My game is still crashing like crazy. I may try the original 4GB launcher to see how things go. Compatibility Mode will simply NOT allow me to use any ENB of any kind without a black screen (with sound), and I'd really like to keep this ENB because my game runs really well with it. My crashes seem to happen out of nowhere while my game is running as smooth as butter.