Well I don't really have that many extra mods, after I installed the core mods from STEP and then most of the mods from STEP Extended it came out to well over 100 ESPs already (somewhere near 140). After that most of my stuff is immersion related, a few overhauls (that are often 5+ ESPs on their own), armors, followers, a few extra quests, some hairs, etc. Most of it I could get rid of, doesn't mean I want to though and it all starts to add up really quickly.
I do appreciate the responses, though it's a little off point from the question I asked. I'm not concerned with whether or not I should merge mods, or remove mods as the case may be, I'm merely asking if it is safe to merge the ESPs in each section into a single ESP per section, or at least a few ESPs per section that way it cuts my mods down from 150-ish before anything after STEP down to 10-30-ish.