I ended up re-downloading my drivers to see if that fixed it, and it did. Windows had one of those forced reboot updates a day or so ago and obviously decided to mess with a few settings somewhere. Knew I should have been suspicious when it said "We have some new features to get excited about".
Also, Thanks Nebulous112, this fixed the SweetFX side of things, although I never had issues with those files before today. Either way everything seems to work fine for now...
