SSE not launching (with and without mods)

[herdustisverypretty]

The game was launching just fine a few weeks ago, and all of a sudden it's not working. I can run other programs through MO (LOOT/xEdit), but SSE and it's launcher will not run through MO now. The game launches fine through Steam, but not through MO at all. I tried deleting the logs like I saw on another post, and then the game ran after that. I quit to add in a couple of mods that I took out just in case they were causing it - now the game won't run again. Tried deactivating all mods (fresh profile with nothing in it) and it still won't run.